Medicals NEWS
Thursday, August 23, 2007
Researchers separate analgesic effects from addictive aspects of pain-killing drugs
Aug. 20, 2007 --
For the first time, pain researchers at the School of Medicine have shown that it's possible to separate the good effects of opiate drugs such as morphine (pain relief) from the unwanted side effects of those drugs (tolerance, abuse and addiction). The investigators, led by Zhou-Feng Chen, Ph.D., associate professor of anesthesiology, psychiatry and molecular biology and pharmacology, report their results online in the Proceedings of the National Academy of Sciences. They found that opiates like morphine don't relieve pain as well in mice genetically engineered to lack neurons that produce a neurotransmitter called serotonin in the central nervous system.
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| Mice developed in the laboratory of Zhou-Feng Chen don't experience relief from pain when given opiate drugs such as morphine. |
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posted by tvnkamal at 9:29 AM
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